Principles Of Research Design And Drug Literature Evaluation
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|Author||: Rajender R. Aparasu,John P. Bentley|
|Editor||: Jones & Bartlett Publishers|
Principles of Research Design and Drug Literature Evaluation is a unique resource that provides a balanced approach covering critical elements of clinical research, biostatistical principles, and scientific literature evaluation techniques for evidence-based medicine. This accessible text provides comprehensive course content that meets and exceeds the curriculum standards set by the Accreditation Council for Pharmacy Education (ACPE). Written by expert authors specializing in pharmacy practice and research, this valuable text will provide pharmacy students and practitioners with a thorough understanding of the principles and practices of drug literature evaluation with a strong grounding in research and biostatistical principles. Principles of Research Design and Drug Literature Evaluation is an ideal foundation for professional pharmacy students and a key resource for pharmacy residents, research fellows, practitioners, and clinical researchers. FEATURES * Chapter Pedagogy: Learning Objectives, Review Questions, References, and Online Resources * Instructor Resources: PowerPoint Presentations, Test Bank, and an Answer Key * Student Resources: a Navigate Companion Website, including Crossword Puzzles, Interactive Flash Cards, Interactive Glossary, Matching Questions, and Web Links From the Foreword: "This book was designed to provide and encourage practitioner’s development and use of critical drug information evaluation skills through a deeper understanding of the foundational principles of study design and statistical methods. Because guidance on how a study’s limited findings should not be used is rare, practitioners must understand and evaluate for themselves the veracity and implications of the inherently limited primary literature findings they use as sources of drug information to make evidence-based decisions together with their patients. The editors organized the book into three supporting sections to meet their pedagogical goals and address practitioners’ needs in translating research into practice. Thanks to the editors, authors, and content of this book, you can now be more prepared than ever before for translating research into practice." L. Douglas Ried, PhD, FAPhA Editor-in-Chief Emeritus, Journal of the American Pharmacists Association Professor and Associate Dean for Academic Affairs, College of Pharmacy, University of Texas at Tyler, Tyler, Texas
|Author||: Rajender R. Aparasu,John Paul Bentley|
Principles of Research Design and Drug Literature Evaluation is a unique resource that provides a balanced approach covering critical elements of clinical research, biostatistical principles, and scientific literature evaluation techniques for evidence-based medicine. This accessible text provides comprehensive course content that meets and exceeds the curriculum standards set by the Accreditation Council for Pharmacy Education (ACPE). Written by expert authors specializing in pharmacy practice and research, this valuable text will provide pharmacy students and practitioners with a thorough understanding of the principles and practices of drug literature evaluation with a strong grounding in research and biostatistical principles.Principles of Research Design and Drug Literature Evaluation is an ideal foundation for professional pharmacy students and a key resource for pharmacy residents, research fellows, practitioners, and clinical researchers.FEATURES* Chapter Pedagogy: Learning Objectives, Review Questions, References, and Online Resources * Instructor Resources: PowerPoint Presentations, Test Bank, and an Answer Key* Student Resources: a Navigate Companion Website, including Crossword Puzzles, Interactive Flash Cards, Interactive Glossary, Matching Questions, and Web LinksFrom the Foreword:"This book was designed to provide and encourage practitioner's development and use of critical drug information evaluation skills through a deeper understanding of the foundational principles of study design and statistical methods. Because guidance on how a study's limited findings should not be used is rare, practitioners must understand and evaluate for themselves the veracity and implications of the inherently limited primary literature findings they use as sources of drug information to make evidence-based decisions together with their patients.The editors organized the book into three supporting sections to meet their pedagogical goals and address practitioners' needs in translating research into practice.Thanks to the editors, authors, and content of this book, you can now be more prepared than ever before for translating research into practice."L. Douglas Ried, PhD, FAPhAEditor-in-Chief Emeritus, Journal of the American Pharmacists AssociationProfessor and Associate Dean for Academic Affairs, College of Pharmacy, University of Texas at Tyler, Tyler, Texas
|Author||: Patrick M. Malone,Karen L. Kier,John Stanovich|
|Editor||: McGraw Hill Professional|
Extensive coverage of the Internet as a source of and distribution means for drug information, and detailed sections on evaluating medical literature from clinical trials Audience includes Pharmacists, Pharmacy students and Pharmacy schools Updated to include using PDAs for medication information Covers the ethical and legal aspects of drug information management Nothing else like it on the market
|Author||: Phyllis G. Supino,Jeffrey S. Borer|
|Editor||: Springer Science & Business Media|
Principles of Research Methodology: A Guide for Clinical Investigators is the definitive, comprehensive guide to understanding and performing clinical research. Designed for medical students, physicians, basic scientists involved in translational research, and other health professionals, this indispensable reference also addresses the unique challenges and demands of clinical research and offers clear guidance in becoming a more successful member of a medical research team and critical reader of the medical research literature. The book covers the entire research process, beginning with the conception of the research problem to publication of findings. Principles of Research Methodology: A Guide for Clinical Investigators comprehensively and concisely presents concepts in a manner that is relevant and engaging to read. The text combines theory and practical application to familiarize the reader with the logic of research design and hypothesis construction, the importance of research planning, the ethical basis of human subjects research, the basics of writing a clinical research protocol and scientific paper, the logic and techniques of data generation and management, and the fundamentals and implications of various sampling techniques and alternative statistical methodologies. Organized in thirteen easy to read chapters, the text emphasizes the importance of clearly-defined research questions and well-constructed hypothesis (reinforced throughout the various chapters) for informing methods and in guiding data interpretation. Written by prominent medical scientists and methodologists who have extensive personal experience in biomedical investigation and in teaching key aspects of research methodology to medical students, physicians and other health professionals, the authors expertly integrate theory with examples and employ language that is clear and useful for a general medical audience. A major contribution to the methodology literature, Principles of Research Methodology: A Guide for Clinical Investigators is an authoritative resource for all individuals who perform research, plan to perform it, or wish to understand it better.
|Author||: Yardlee S. Kauffman,Daniel M. Witt|
"The purpose of this work is to provide Post Graduate Year 1 (PGY1) and Post Graduate Year 2 (PGY2) pharmacy residents with an elementary introduction to the research process and overview of steps that should be considered when initiating a research project. For pharmacy residents, conducting a research project from start to finish is mandatory for ASHP's residency accreditation standards. For many pharmacy residents, especially those in their first year of postgraduate training, research presents a number of daunting hurdles-how to find and evaluate research opportunities, study design, appropriate statistical analysis, and the IRB are all outside the typical pharmacist's comfort zone. Additionally, residency programs vary nationally with respect to providing support to residents throughout the stages of the research process. This book will be a primer that pharmacy residents can turn to when they need to know how to design, start, and complete a research project successfully. By providing clear steps and even tools that can be adapted for the reader's needs, this book will remove the mystique around research and biostatistical analysis, making it accessible to all"--
|Author||: Michael K. Pugsley,Michael J Curtis|
This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to academia, industry and regulatory authorities. It provides readers with a definitive collection of topics containing essential information on the latest industry guidelines and overviews current and breakthrough topics in both functional and molecular pharmacology. An additional novelty of the book is that it constitutes academic, pharmaceutical and biotechnology perspectives for Safety Pharmacology issues. Each chapter is written by an expert in the area and includes not only a fundamental background regarding the topic but also detailed descriptions of currently accepted, validated models and methods as well as innovative methodologies used in drug discovery.
|Author||: Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson, Jr.|
|Editor||: Academic Press|
Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK
|Author||: Rajender R. Aparasu|
|Editor||: Pharmaceutical Press|
This text provides the theory and practice for conducting pharmaceutical policy research. It covers all aspects of scientific research from conceptualising to statistical analysis. It also provides scientific basis and a good understanding of the principles and practice of conducting pharmaceutical policy research.
|Author||: Benjamin E. Blass|
|Editor||: Academic Press|
Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. Provides a clear explanation of how the pharmaceutical industry works, as well as the complete drug discovery and development process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual property Includes a new chapter on the discovery and development of biologics (antibodies proteins, antibody/receptor complexes, antibody drug conjugates), a growing and important area of the pharmaceutical industry landscape Features a new section on formulations, including a discussion of IV formulations suitable for human clinical trials, as well as the application of nanotechnology and the use of transdermal patch technology for drug delivery Updated chapter with new case studies includes additional modern examples of drug discovery through high through-put screening, fragment-based drug design, and computational chemistry
|Author||: Colin Robson|
How can evaluation be used most effectively, and what are the strengths and weaknesses of the various methods? Colin Robson provides guidance in a clear and uncluttered way. The issue of collaboration is examined step-by-step; stakeholder models are compared with techniques such as participatory evaluation and practitioner-centred action research; ethical and political considerations are placed in context; and the best ways of communicating findings are discussed. Each chapter is illustrated with helpful exercises to show the practical application of the issues covered, making this an invaluable introduction for anyone new to evaluation.
|Editor||: Educreation Publishing|
This comprehensive Handbook is aimed at both academic researchers and practitioners in the field of research. The book's 8 chapters, provide in-depth coverage of research methods based on the revised syllabus of various universities especially considering the students of under graduate, post graduate and doctorate level. This book is a product of extensive literature survey made by the authors. The authors have made sincere efforts to write the book in simple language. The book comprises all the aspects according to new syllabus of PCI and APJ Abdul Kalam Technical University, Lucknow. Though this book is intended for the use of pharmacy students of any level yet it can also be useful to students of applied fields and medical students. The book deals with interdisciplinary fields such as finding research problems, writing research proposals, obtaining funds for research, selecting research designs, searching the literature and review, collection of data and analysis, preparation of thesis, writing research papers for journals, citation and listing of references, preparation of visual materials, oral and poster presentation in conferences, minutes of meetings, and ethical issues in research. At the end of every chapter and book some questions related to chapter have been mentioned for the support of students to understand the subject. Valuable suggestions for the improvement of this book are most welcome.
|Author||: Dixon Thomas|
Clinical Pharmacy Education, Practice and Research offers readers a solid foundation in clinical pharmacy and related sciences through contributions by 83 leading experts in the field from 25 countries. This book stresses educational approaches that empower pharmacists with patient care and research competencies. The learning objectives and writing style of the book focus on clarifying the concepts comprehensively for a pharmacist, from regular patient counseling to pharmacogenomics practice. It covers all interesting topics a pharmacist should know. This book serves as a basis to standardize and coordinate learning to practice, explaining basics and using self-learning strategies through online resources or other advanced texts. With an educational approach, it guides pharmacy students and pharmacists to learn quickly and apply. Clinical Pharmacy Education, Practice and Research provides an essential foundation for pharmacy students and pharmacists globally. Covers the core information needed for pharmacy practice courses Includes multiple case studies and practical situations with 70% focused on practical clinical pharmacology knowledge Designed for educational settings, but also useful as a refresher for advanced students and researchers
|Author||: Irving Rootman,Michael Goodstadt|
|Editor||: WHO Regional Office Europe|
This book is the result of the WHO European Working Group on Health Promotion Evaluation which examined the current range of qualitative and quantitative evaluation methods to provide guidance to policy-makers and practitioners. It includes an extensive c
|Author||: J. Glenn Forister,J. Dennis Blessing|
|Editor||: Jones & Bartlett Publishers|
Introduction to Research and Medical Literature for Health Professionals, Fourth Edition is included in the 2015 edition of the essential collection of Doody's Core Titles. Introduction to Research and Medical Literature for Health Professionals, Fourth Edition is an essential resource to help students, faculty, and practitioners understand the research process, interpret data, comprehend results, and incorporate findings into practice. From choosing a research project and developing the research process design, to systematically gathering information, analyzing, interpreting data, differentiating among conflicting results, and finally understanding the overall evaluation, Introduction to Research and Medical Literature for Health Professionals, Fourth Edition will help students and practitioners develop research skills to acquire and contribute knowledge that benefits their patients. NEW TO THE FOURTH EDITION NEW Chapter: Statistics in Health Care NEW Chapter: Systematic Reviews Heavily revised chapter on the regulatory protection of human subjects, providing readers with a comprehensive look at the workings of the institutional review board Completely rewritten chapter on qualitative research Learning Objectives at the beginning of each chapter, presenting the chapter's desired outcomes to the reader Instructor Resources: Instructor's Manual, Slides in PowerPoint format, Test Bank Each new print copy includes Navigate 2 Advantage Access that unlocks a comprehensive and interactive eBook, student practice activities and assessments, a full suite of instructor resources, and learning analytics reporting tools.
|Author||: Anol Bhattacherjee|
This book is designed to introduce doctoral and graduate students to the process of conducting scientific research in the social sciences, business, education, public health, and related disciplines. It is a one-stop, comprehensive, and compact source for foundational concepts in behavioral research, and can serve as a stand-alone text or as a supplement to research readings in any doctoral seminar or research methods class. This book is currently used as a research text at universities on six continents and will shortly be available in nine different languages.
|Author||: Marta Peris-Ortiz,Jaime Alonso Gómez,Patricia Marquez|
This book examines the different ways companies can develop and design social innovation. Combining technological and social perspectives, the contributors present emerging research on social innovation from different sectors such as entrepreneurship, education and energy. Collectively, the authors demonstrate the ways in which social innovation can drive sustainability and development in regions around the world. All societies are characterized by their political, economic and social institutions, as well as by how they utilize technology. The social innovations with the highest importance are those which modify existing institutions or create new ones, and based on their magnitude, they can be considered as radical or incremental. For example, when Joseph Chamberlain encouraged workers to organize in order to achieve universal male suffrage in Great Britain in 1885, this was a considered a radical innovation for British society, which in turn changed its political framework. Social innovations may be based on intelligence and commitment, on technology or on social entrepreneurship in its most open forms. In addition, social innovations can be classified into those which correspond to an entire country or region, a field (e.g., education) or a sector (e.g., entrepreneurship, technology, social reform). Featuring contributions on topics such as agro-food, smart cities, higher education, gender equality and sports, this book is ideal for academics, students, scholars, professionals and policy makers in the areas of innovation, entrepreneurship, sustainability and regional development.
|Author||: John Talbot,Jeffrey K. Aronson|
|Editor||: John Wiley & Sons|
The detection and evaluation of adverse drug reactions is crucial for understanding the safety of medicines and for preventing harm in patients. Not only is it necessary to detect new adverse drug reactions, but the principles and practice of pharmacovigilance apply to the surveillance of a wide range of medicinal products. Stephens' Detection and Evaluation of Adverse Drug Reactions provides a comprehensive review of all aspects of adverse drug reactions throughout the life cycle of a medicine, from toxicology and clinical trials through to pharmacovigilance, risk management, and legal and regulatory requirements. It also covers the safety of biotherapeutics and vaccines and includes new chapters on pharmacogenetics, proactive risk management, societal considerations, and the safety of drugs used in oncology and herbal medicines. This sixth edition of the classic text on drug safety is an authoritative reference text for all those who work in pharmacovigilance or have an interest in adverse drug reactions, whether in regulatory authorities, pharmaceutical companies, or academia. Praise for previous editions "This book presents a comprehensive and wide-ranging overview of the science of pharmacovigilance. For those entering or already experienced in the pharmaceutical sciences, this is an essential work.” - from a review in E-STREAMS "...a key text in the area of pharmacovigilance...extensively referenced and well-written...a valuable resource..." - from a review in The Pharmaceutical Journal
|Author||: Institute of Clinical Research|
In an arena which has seen rapid change over the past decade, this work provides a comprehensive and up-to-date guide to the planning, organization and management of clinical trials.